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Adenosine 1 significantly reduced infarct size when administered at the end of sustained ischemia and showed enhanced cardioprotection compared to adenine 25

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Furthermore, effector genes GZMB , GNLY , GZMA , PRF1 , IL-2 , IFN as well as the master regulator of exhaustion TOX were significantly downregulated in rapamycin-treated CAR T products (Fig