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This one might seem counterintuitive, since semaglutide is a medication that could theoretically affect the heart

High-dose oral B12 can still be effective for those with mild absorption problems

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Non-Medical, Reversible Causes Some causes are related to lifestyle or environmental factors and can often be reversed: Dehydration Smoking Living at high altitude Carbon monoxide exposure Use of certain drugs (anabolic steroids or erythropoietin-stimulating agents) Underlying Medical Conditions In some cases, a high hemoglobin level may be linked to an underlying condition: Chronic obstructive pulmonary disease (COPD) Emphysema Congenital heart disease Pulmonary fibrosis Kidney cancer Liver cancer Polycythemia vera (a rare blood disorder) If your hemoglobin levels remain elevated over time, its important to follow up with your GP to determine the underlying cause and whether any treatment is needed