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Pre-treatment with insulin-like growth factor-I partially ameliorates 5-fluorouracil-induced intestinal mucositis in rats

Safety, tolerability, and efficacy results trial of AVP-923 in PBA investigators

Shungu Once the process starts, it can be hard to tell what is causing what as the mitochondrial and oxidative stress problems feed into each other: In our study of primary mitochondrial disorders (e.g., MELAS), we have found a cortical GSH deficit that seems to be even bigger than in ME/CFS, meaning that mitochondrial dysfunction and oxidative stress co-exist and likely potentiate and sustain each other in such disorders

Rudnicka E, Suchta K, Grymowicz M, Calik-Ksepka A, Smolarczyk K, Duszewska AM, Smolarczyk R, Meczekalski B

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