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One study reviewed the impact of the gutbone axis in the context of aging on phenomena constituting osteoporosis and hematopoietic hypoplasia (100)

For example exposure to metals, chemical and xenobiotic compounds, air pollution, benzene, organic pollutants, and radiation can induce mutations that contribute to the development of cancer especially during embryonic stages, environmental factors have a more crucial impact on the genome and even can increase the risk of cancer in F 1 , F 2 and F 3 generation [33]

ROS generation can affect DNA, lipids, proteins and carbohydrates 15

For the acute and chronic treatment of patients with an inborn error of metabolism which results in secondary carnitine deficiency

Serum-based analyses may also prove useful for early clinical decision making, most critically in determining the need for a head CT after TBI [40]