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A multi-society Delphi consensus statement on a new fatty liver disease nomenclature was published in 2023, thereby introducing the term metabolic dysfunction-associated steatotic liver disease (MASLD) and effectively letting go of the term NAFLD and MAFLD ( Figure 1 Dysbiosis of the gut microbiota has been consistently linked to both obesity and T2DMtwo metabolic disorders closely associated with MASLD

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Although metformin is not the first choice for the treatment of MASLD, it is effective in improving body weight, lipids and glucose metabolism in patients with MASLD or MASLD combined with T2DM (245)