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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Dumitrescu A.M., Liao X.-H., Abdullah M.S.Y., Lado-Abeal J., Majed F.A., Moeller L., Boran G., Schomburg L., Weiss R.E., Refetoff S

Aberrant cell cycle progression leads to chromosomal abnormalities and embryonic arrest, making cell cycle regulation biomarkers important predictors of embryo competence [395]

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This could be due to elevated Prohibitin 1(PHB1) expression in GCs of EMS patients

When combined with chronic low grade inflammation, this proinflammatory pleiotropic cytokine might switch from self recognition to loss of self-recognition or autoimmune status (De Benedetti et al., 2021)