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Gut 1995;37:11920

Dividing glutamine intake throughout the day may enhance bioavailability and reduce gastrointestinal symptoms associated with higher single doses. Newsholme, Journal of Nutrition Sample Split-Dosing Schedule Do You Need to Cycle Off

In addition, glutamine deprivation inhibits the activity of invading CD8 + T lymphocytes in HCC through mitochondrial damage and apoptotic pathways [122]