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Former studies revealed that favipiravir was successfully used to treat infections associated with rabies, Lassa virus, and Ebola virus (Shiraki and Daikoku, 2020)
Crucially, this study shifted the scientific paradigm from a simple model of "glutathione depletion" to a model of an "overwhelmed compensatory mechanism." The discovery that circulating immune cells in these patients actually have elevated glutathione levelswhile simultaneously suffering from a severe depletion of other protective enzymes like SOD2revealed that the cells are desperately, and unsuccessfully, trying to fight off a catastrophic level of oxidative damage
66 INCORPORATING ADVANCE CARE PLANNING IN ADULTS WITH DECOMPENSATED CIRRHOSIS AT LIVER TRANSPLANT CENTERS: A NURSING-LED EDUCATIONAL INITIATIVE Janet Gripshover 1,2 , Rita DAoust 1 , Deborah Baker 1 and Arpan Arun Patel 3 , (1)Johns Hopkins University, (2)University of California Los Angeles, (3)Greater Los Angeles VA Healthcare System Background: Clinician inexperience with advanced care planning (ACP) is a barrier to patient-centered care for adults with decompensated cirrhosis (DC) at liver transplant centers
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