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Excessive shortening triggers persistent DNA damage response or genomic instability, causing cellular senescence, and is also strongly linked to lifespan (Whittemore et al., 2019

M.MaherS

Monomeric prolactin is the most common form, but serum prolactin can be elevated due to the presence of aggregates with low biological activity, such as big-big prolactin, leading to so-called macroprolactinemia