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Although some genes involved in the platelet pathway were upregulated after PPE, they were not altered by necroptosis deficiency, indicating that AAA protection might be primarily mediated through reduced SMC necroptosis and inflammation

The redox status of the cell has a large effect on disulfide bond formation, protein folding, and dimerization of multidrug resistance (MDR) proteins such as MDR-1 (Liu et al., 2016), thereby increasing drug resistance (Tivnan et al., 2015)

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