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While preparing this manuscript for submission, a study based exclusively in in vitro assays was published showing that the addition of 25 M BSO or the use of tools to delete GCLC inhibits the growth of Burkitt lymphoma cell lines under 2D culture conditions [42], seemingly suggesting a comparable susceptibility to glutathione starvation between TICs and differentiated tumor cells

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found that Gln is a key amino acid in the regulation of glucose stability and insulin sensitivity, and the level of Gln affects the inflammatory response of skeletal muscle and regulates the expression of the adaptive protein GRB10, an insulin signaling inhibitor

AIIB2-induced inhibition and scTS2/16 enhancement of growth (compared with the medium without antibody) were observed in all cases (fold increases in examples shown in Fig

Liver detoxification support Physiological significance of glutathione S-transferases