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Iron uptake and the labile iron pool (LIP) Extracellular Fe3+ typically binds to transferrin and enters cells via endocytosis through transferrin receptor 1 on the cell membrane

Furthermore, elesclomol significantly reduced the spare respiratory capacity of mitochondria but left basal and ATP-linked respiration unaffected, suggesting that the copper may target TCA cycle components directly, without disrupting ETC activity or ATP generation

Of these, Glu4.2 also co-expressed Ramp3 across all species (see Extended Data Figs

-Galactosidase hydrolyzes lactose to form glucose and galactose, which enter glycolysis, and also catalyzes the transgalactosylation of lactose to isolactose, which can be cleaved to monosaccharides