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In addition, mitochondrial shrinkage and increased membrane density were observed, indicating that SAL induces ferroptosis and exacerbates neurotoxicity in both in vivo and in vitro PD models

Upon oxidation, it forms a disulfide-bonded dimer (GSSG)

MDA is generated through the reaction of ROS with polyunsaturated fatty acids in cellular membranes and is considered an indicator of cellular damage and inflammation [131]

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