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Front Endocrinol (Lausanne) (2016) 7:131

Ciancarelli, I., Tozzi-Ciancarelli, M., Massimo, C

Crit Care Med 2001

Furthermore, studies have reported an aberrant activation of NRF2, a key antioxidant transcription factor involved in the regulation of critical antioxidants including glutathione, SOD, and CAT, leading to reduced antioxidant capacity (Hirayama et al., 2020)