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doi: 10.3389/fimmu.2022.977235 118 RyanWLCarverMJ

Research indicates it can help heal damage caused by factors like alcohol and nonsteroidal anti-inflammatory drugs (NSAIDs) and may improve conditions associated with "leaky gut" syndrome by stabilizing intestinal permeability

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The 2 individual patient-reported components (stool frequency and rectal bleeding) are part of the Mayo score and were not powered for statistical significance Correlation of depicted PROs to Week 6 and Week 52 primary end points was not evaluated in the analysis GEMINI I TRIAL EXPLORATORY END POINTS: PATIENT-REPORTED OUTCOMES Overall population compared with placebo Not powered for statistical significance