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Retrieved 21 December 2018

[PMC free article: PMC4841927] [PubMed: 27075905] 31

These signaling cascades produce tissue-specific effects: hepatic IGF-1 production for endocrine growth signaling, muscle protein synthesis and glucose uptake, adipose tissue lipolysis, bone formation, and immune cell modulation

Not biological outcomes.) Mechanistic Notes (Research Context Only) In laboratory settings, Vitamin B12 is studied for its interaction with: Methylationcycle enzymes such as methionine synthase Cellularenergy pathways involving fattyacid and aminoacid metabolism Biochemical cascades associated with redbloodcell formation models Neurochemicalresponse mechanisms linked to cobalamindependent signaling These statements describe mechanistic interest , not biological effects in humans or animals