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This configuration enhances antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis, thereby strengthening the immune response against BCMA-expressing multiple myeloma cells

In contrast, the Met-inactive aMsD4-C6 did not induce proliferation, suggesting that the restored proliferation of HCC827 cells resulted from Met activation by the dimeric macrocycles

Consequently, by mitigating oxidative stress and enhancing vascular function, NAD + holds promise as a therapeutic target for blood pressure regulation

The scale-up of small-molecule manufacturing is also fundamentally more straightforward than peptide scale-up

SASP: The senescence-associated secretory phenotype refers to molecules released by senescent cells that both help them survive, and that signal immune cell clearance