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doi: 10.1530/JOE-18-0278 51 ElzeinSGates GoodyerC

HMG-CoA reductase inhibitors inhibit endothelial exocytosis and decrease myocardial infarct size

This paper comprehensively reviews IRAK4 and its family members physiological functions, systematically examines the IRAK familys roles in the IL-1R/TLR pathway, with a focus on IRAK4, analyzes IRAK4s specific role in HS, strengthening the theoretical basis for using IRAK4-targeted drugs