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Enzyme-capacity constraint flux balance analysis (ecFBA) and flux-sum analysis To investigate metabolic states under various conditions, we utilized the iCHO2291 model, a comprehensive reconstruction of the CHO cell metabolic network 33 , adapted by incorporating experimentally measured uptake and secretion rates as boundary constraints for each condition, with exchange flux bounds for unmeasured or unexpected metabolites set to zero to prevent artificial nutrient uptake, while adjusting the bounds for glucose uptake, lactate secretion, and the biomass reaction to 10% of their measured rates to accommodate potential experimental errors, a range determined to effectively simulate physiological behavior

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Glutathione lm trng da ton thn thng qua c ch, gip da tng cng to ra sc t melanin sng v ngn chn to ra hc t melanin (melanin en), bng cch can thip vo qu trnh chuyn ha v ngn nga hot ng ca enzyme tyrosinase, gip lm o ngc tin trnh tng hp sc t melanin sng thay v tng hp cc sc t melanin ti, kt qu l da dn trng sng v u mu hn

found that -HB could inhibit the apoptosis of dopaminergic cells that were exposed to MPTP in relation to the upregulation of Bcl-2/Bax mRNA

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