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Indeed, the scRNA-seq analysis of the G6PDH-deficient growth plate showed a sequential stage-dependent profile, starting with an increase in protein processing and proteasome activation and followed by ferroptosis induction

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The bronchodilator bambuterol, a dimethylcarbamate prodrug of terbutaline (Figure 12), has a significantly reduced first-pass metabolic effect due to the protection of the metabolically susceptible phenolic hydroxyl group in the drug structure

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