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The concentration of each analyte in the samples was determined from calibration curves by using the peak area ratio of the analyte to its corresponding isotope internal standard

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Further longitudinal studies using larger samples with longer antipsychotic treatment are warranted to understand the exact mechanism of L-carnitine metabolites in cognitive improvement in schizophrenia

The profound, crushing fatigue that characterizes these illnesses is not simply a matter of being "tired"it is a fundamental crisis of cellular energy production