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Paradoxically, however, reduced expression of specific mitophagy regulators, including PRKN [58] and BNIP3 [60], has been linked to worse prognosis in PDAC, underscoring the limitations of monogenic biomarkers in reflecting the functional state of mitophagy

Berezina, V.V

11 Although each group assigned a different name to the protein (FRAP, 8 RAFT1, 9 or RAPT1 10 ), the term mTOR 11 for mammalian target of rapamycin ultimately became the accepted standard in mammals and other eukaryotes

Age Old age is the primary risk factor for the evolution of AD