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These heritable molecular alterations regulate gene expression patterns and influence key pathophysiological processes, including ovarian dysfunction, hormonal dysregulation, and insulin signaling impairment, without modifying the underlying DNA sequence (48, 49)

Trends in Analytical Chemistry, 88 , 124

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This strategy significantly reduces the guesswork in experimental screening while greatly minimizing the use of resources, offering a smart and budget-friendly solution for drug development (Guo et al., 2023

200 Angiogenic factors in GBM are regulated by oncogene activation, tumor suppressor loss, and hypoxia