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Recent research has reported that some drugs in combination with antibiotics have displayed synergistic killing against resistant bacteria ( Escherichia coli , and L-alanine metabolism conferred aminoglycoside resistance via Na + -NQR ( Glutathione (GSH) is an antioxidant synthesized in most Gram-negative bacteria and a few Gram-positive bacteria ( Escherichia coli by neutralizing antibiotic-induced oxidative stress, increasing the efflux of antibiotics, and promoting acid shock survival ( However, it is not known whether GSH can restore the activity of meropenem against CRKP

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The deduced amino acid sequences of AsGGT1 , AsGGT2 , and AsGGT3 possessed the conserved threonine residue required for autocatalytic processing and the amino acid residues necessary for GGT activity, which were previously identified by biochemical and structural analyses of GGTs from humans and E

Kurita, K., Ohta, H., Shirakawa, I., Tanaka, M., Kitaura, Y., Iwasaki, Y., Matsuzaka, T., Shimano, H., Aoe, S., Arima, H., Ogawa, Y., Ito, A., & Suganami, T