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Fermented Okra'scomposition and texture does not have viscosity ('sliminess') of cooked okra

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This poor absorption is driven by extensive first-pass metabolism in the liver and active clearance by P-glycoprotein efflux pumps in the intestines, which actively push the berberine back out into the gut lumen

To mechanistically delineate STEAP3 deficiency-driven ferroptosis via iron overload, deferoxamine (DFO) was employed to chelate intracellular labile iron pools