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Trx is a widely distributed small dithiol protein that contains 104 amino acids, including one disulfide bridge, two SH groups, and a conserved active site (Trp-Cys-Gly-Pro-Cys) [119]

(2E)-3-(1 ,3-benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide can also be synthesized directly from (2E)-3-(1 ,3-Benzodioxol-5-yl)-2-propenoic acid and N-phenyltetrahydrofuran- 3-amine with standard amide coupling reagents