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Despite distinct enzymatic defects (MMUT versus propionyl-CoA carboxylase deficiency), both disorders exhibit neurological sequelae, including seizures, developmental delay, and structural brain abnormalities (Ballhausen et al

Androgen modulation of coregulator expression in prostate cancer cells

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A recent self-transcribing active regulatory region sequencing (STARR-Seq) study identified 12% of AR binding sites at enhancers as constitutively active, 7% as AR-inducible or AR-activated and the remaining 81% as inactive [55]