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We observed neither an NMD-dependent increase in general HIF-1 activity nor a hif-1- dependent increase in NMD activity, indicating that neither NMD nor HIF-1 acts strictly upstream of the other

Ammonium persulfate (100 L, 20%, Sigma) was added while vortexing and continued for 1 min

Curcumin reduced H2O2-and G2385R-LRRK2-induced neurodegeneration

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62 Oxidative stress Oxidative stress is a condition that results in the production of ROS or reactive nitrogen species (RNS) that cannot be adequately addressed by normal antioxidant mechanisms