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Additional experiments conducted on various mammalian cells have indicated that treatment with the purine antimetabolite 6-TG can cause DNA single- and double-strand breaks, as well as chromosomal damage [49, 50]

Richard Lord, who was my post-grad supervisor at the time and is my mentor still, on the risks of having your homocysteine run too low

We suppose that inconsistent results concerning glutathione concentrations in old rats, which were provided by various authors, may by a consequence of subclinical disease which was not taken into account by researchers

However, it took another 26 years to identify and sequence the 41-amino acid peptide that plays a pivotal role in the stress-related pituitary release of ACTH and -endorphin (Vale et al., 1981

When the desensitized GSH I-encoding gene gshA * was cloned, the activity of the mutant GSH I increased tenfold compared with the wild type enzyme