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This condition is often associated with liver disease

Doaei S, Gholami S, Rastgoo S, Gholamalizadeh M, Bourbour F, Bagheri SE, Samipoor F, Akbari ME, Shadnoush M, Ghorat F, Mosavi Jarrahi SA, Ashouri Mirsadeghi N, Hajipour A, Joola P, Moslem A, Goodarzi MO (2021) The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial

Three authors (K.B., C.B., and L.M.) independently searched MEDLINE, Embase, and PsychINFO from 1960 (or 1974 in the case of EMBASE) to March 30th 2023, identifying 159 papers in total (111 with duplicates removed)

It is induced by mutations in the gene encoding 3-hydroxysterol- 7 -reductase (DHCR7), the enzyme catalyzing cholesterol formation by 7-dehydrocholesterol reduction

The Growth Hormone Signaling Story Growth hormone is one of the clearest illustrations of this principle