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Elevated levels of circulating glycylproline, often linked to reduced prolidase activity, may indicate increased collagen degradation or turnover, which is associated with disorders affecting connective tissues, joint health, or skin integrity 40,41

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Although this research was a quasi-experimental study (without a control group) in which the results are just beforeafter comparisons, its findings highlight the possible beneficial effects of this neglected antioxidant in various conditions which have a connection with oxidative stress, the area which remains to be elucidated through further randomised controlled trials