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In this case the poor enzyme efficiency leads to slowed conversion of folic acid and folate into active forms like5-MTHF

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Transgenic lines expressing roGFP2 indicated a change in the glutathione redox potential upon AITC treatment The application of AITC led to stronger responses for the glutathione mutants than for WT, which may suggest an essential role for this tripeptide in the AITC-induced physiological responses