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Description

Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4

Elevated systemic oxidative stress can lead to notable fibrinogen oxidation and structural alterations, which are associated with impaired fibrin polymerization and enhanced resistance to plasmin-induced lysis

Chamoun K, Kantarjian H, Atallah R, Gonzalez GN, Issa GC, Rios MB, Garcia-Manero G, Borthakur G , Ravandi F, Jain N, Daver N, Konopleva M, DiNardo CD, Kadia T, Pemmaraju N, Jabbour E, Cortes J