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HO-1 can degrade haem into ferrous iron, and overexpression of HO-1 can alleviate hypertrophy, fibrosis and oxidative stress in a failing heart and promote neovascularization [116]

Chronic renal failure and uremia represent states wherein high blood levels of Hcy are seen [70], and with decline in function these patients become more and more hyperhomocysteinemic [93]

ROS, generated by oxidative stress, can trigger melanogenesis pathways, increasing melanin production

After incubation with the dye for 30 min, microscopy images were obtained using the Keyence Fluorescent Microscope BZ-X800 (Keyence, IL)

Glutamic pyruvate transaminase Gpt2 promotes tumorigenesis of breast cancer cells by activating sonic hedgehog signaling