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Some studies have shown that PD patients suffer from constipation for over 20 years before the onset of motor symptoms [111]

Flavonoids like quercetin, catechins, and anthocyanins, as well as phenolic acids such as caffeic and ferulic acids, offer significant antioxidant benefits

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doi: 10.3390/foods12071490 118

Moreover, the resistance of PLGA nanoparticles encapsulating DDA-GSH-AuNCs to photobleach upon continuous laser irradiation was evaluated in comparison with conventional fluorescent dyes: Nile red and fluorescein (relatively stable and labile dyes to photobleaching, respectively) 51