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At present, the most commonly used methods are gene-modified bacteria and surface-modified bacteria, and some natural bacteria such as Lactobacillus (LAB) and Escherichia coli Nissle1917 (EcN) had been proved to be safe clinically (49, 50)

Clemmons DR, Moses AC, McKay MJ et al (2000) The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity

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Lipotropic protocols show best results when you can isolate fat loss from water retention and lean mass changes

These self prescribed treatments are illegal and putting people at risk