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Methods Statistics and reproducibility Many of the analyses in this study involve computation of root mean square errors (RMSE) and Pearson correlation coefficients (PCC) or R -values over mixtures, either experimentally generated ones or in-silico, in both cases, the mixing fractions are known

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For the primary cells, 2 subsets of CLL lymphocytes were tested: proliferating cells (supplemented with CD40 ligand and interleukin-4) and quiescent cells