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Methods: Ten-week-old Mdr2 -/- mice with congenital PSC-like progressive biliary disease, and healthy wild-type littermates (WT) mice enrolled as control fed with chow diet or DDC (3,5-diethoxycarbonyl-1,4-dihydrocollidine) were subjected to either modified retrograde biliary instillation or hydrodynamic tail vein injection of sleeping beauty transposon-transposase plasmid system with activated forms of AKT (myr-AKT) and Yap (YapS127A) protooncogenes (SB AKT/YAP1)

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Seiler A, Schneider M, Frster H, Roth S, Wirth EK, Culmsee C, et al

PHOTOSENSITIVE: Avoid direct sunlight or UV rays for 12-24 hours after topical application to prevent skin sensitivity

Snegur and coworkers prepared the new ferrocenylethyl benzotriazole 20 and studied it concerning its in vivo activity in lung cancer xenografts via the subrenal capsular assay (SCA) in comparison with cisplatin (Fig