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Once released, these cholesterol precursors interact with LDLR of T cells, driving their polarization towards a Th17 phenotype through activation of the transcription factor RORt, which has immunosuppressive functions ( 4.1.4 Prostate cancer Prostate cancer, which accounts for 7.3% of all cancers diagnosed worldwide, is the second most common cancer in men

Shortened telomeres are associated with cellular aging, and compounds that influence this pathway are of growing interest in longevity medicine

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In future studies, measuring erythrocyte levels of these amino acids could be more informative than plasma levels, particularly if investigating changes due to supplementation