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Other considerations documented for tirzepatide in its FDA labeling include injection-site reactions, decreased appetite, and warnings such as the risk of thyroid C-cell tumors observed in rodents (a boxed warning) and pancreatitis and gallbladder events

Crows feet are small wrinkles around the eyes that are caused by facial expressions, especially eye movements like squinting or laughing

He'd fall asleep fine and wake up not quite refreshed, a subtle but persistent shift in sleep architecture

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