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Ishida, T

Ferroptosis is a novel form of PCD, which exhibits several pathophysiological features reminiscent of those seen in SLE, including intracellular iron accumulation, mitochondrial dysfunction, lipid metabolism disorders, and regulation by DAMPs ( Table 1 )

The activity of SOD was found to be decreased with a consequent increase of the SO anion in the offspring of undernourished dams, which also indicates decreased formation of H 2 O 2

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Importantly, tumor cells isolated from CDDO-Me-treated mice did not show significant signs of acquired resistance to DKFZ-682 (Fig