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Although M2 macrophages have been studied for their central role in fibrosis and cell proliferation during tissue repair [42, 49], our study provides strong evidence, which was previously unidentified, that they may also have a promoting effect on myofibroblast differentiation of LR-MSCs

Our findings indicate that patients with diabetes with cardiovascular comorbidities exhibit the lowest plasma levels of PA, and similarly low levels are observed in patients with diabetes overall

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