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Endothelium-dependent contractions and endothelial dysfunction in human hypertension

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During ischemia-reperfusion injury, NOX overexpression and enhanced activity contribute to ROS generation, subsequently promoting cellular ferroptosis

Inspired by aforementioned reasons and as a part of the ongoing work in our research groups aimed at the search of novel antidepressants 6,34 with neuroprotective mechanism, we started a scaffold hopping campaign of Agomelatine in silico

Second, it slows gastric emptying, meaning food stays in your stomach longer and you feel full for extended periods after smaller meals