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Dowdle et al

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Ingredients: Each capsule contains: N-Acetylcysteine (NAC) - 600mg Selenium - 50mcg from SelenoExcell High Selenium Yeast (Saccharamyces cerevisiae) SelenoExcell is a registered trademark of Cypress Systems, Inc

2.9 Cell culture and treatment Mouse colon epithelial cells (MCECs) were cultured in high-glucose Dulbeccos Modified Eagle Medium, supplemented with 10% fetal bovine serum and 1% penicillin-streptomycin (P/S), in a humidified incubator with 5% CO 2 at 37C

Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression