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Although the study revealed that low-to-high levels of vitamin C supplementation were associated with a reduced risk of glaucoma, no direct association was found between serum vitamin C concentrations and the prevalence of glaucoma ( p = 0.034), while there was no significant correlation with the severity of the disease

10.1038/s41467-019-09722-9

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Cells were cultured in high glucose (25 mM) if not mentioned otherwise, supplemented with pyruvate to allow for NADH to NAD + recycling and pyruvate-dependent aspartate biosynthesis 77,78

Science 280 (5369), 16071610