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n = 3 animals analyzed in one experiment

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Additionally, there was no significant change in the intensity ratio observed in the presence of GSSG, which confirms the specificity of FLIP-G with reduced form (GSH) over the oxidized one (GSSG) in vivo (Fig

Despite these advances, several challenges remain in translating ferroptosis-targeted therapies into clinical practice

We focused on the metabolism of sulfur compounds, which are greatly involved in the redox action in the body, and conducted a comprehensive analysis of 87 types of sulfur metabolites (sulfur index analysis) in a total of four groups: the Con-DSS group, the Si-DSS group, the control group, and Si groups