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That may be a rational design for local GI exposure , where systemic bioavailability may not even be the primary objective

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BioRender Template Dopamine's PKA/cAMP pathway intracellular signaling cascade Description This template ilustrates one of dopamine's various intracellular signaling cascades, the PKA/cAMP pathway

Another proposed mechanism of vancomycin-associated nephrotoxicity is intracellular accumulation of vancomycin

Most patients see consistent 12 lb/week loss over a 12-week course