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It works by stimulating receptors in the brainstem, which reduces sympathetic nervous system activity

[8] [25] Although no significant increased risk of cancer in human treatment with coal tar shampoos have been found, caution is advised since coal tar is carcinogenic in animals, and heavy human occupational exposures do increase cancer risks

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The results showed that patients with a mean baseline body weight of 106.9 kg who were treated with CagriSema (2.4/2.4 mg) achieved 22.7% weight loss after 68 weeks, compared to 11.8% of those treated with cagrilintide 2.4 mg monotherapy and 16.1% of those treated with semaglutide 2.4 mg monotherapy, and to 2.3% of those receiving only the placebo [125]

These molecules are increasingly recognized for their therapeutic value