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260 While the previously mentioned dye colorants showed limited selectivity for thiols, Strongin et al

TRIM59 is up-regulated in gastric tumors, promoting ubiquitination and degradation of p53

doi: 10.1038/s41418-017-0053-8 49 ShenXChenYTangYLuPLiuMMaoTet al

6C and D)

The presence of glutathione in these intermediate conjugate forms of the different methylated forms of arsenic allows these molecules to be exported out of the cells by the ATP-binding cassette multidrug resistance proteins (MDR-C) system [52,53,54,55,56]