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Subsequently, we used limited proteolysis to identify the regions of the polypeptide chain mostly prone to proteolysis and thus the sites of high flexibility or local unfolding 22 (Fig

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Moreover, a greater proportion of participants on retatrutide 8 and 12 mg (7782%) achieved an HbA1c 6.5% compared to placebo (5%) and dulaglutide 1.5 mg (43%)

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Predicting the stability of lyophilized formulations containing a monoclonal antibody and sucrose/trehalose using solid-state NMR spectroscopy

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In pernicious anemia, the immune system attacks a protein called intrinsic factor, which is required for B12 absorption, and it results in low B12 levels

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Many studies are pre-clinical (animal models) or small human trials making it harder to generalize to broad populations, especially those with complex sleep disorders such as sleep apnea or chronic insomnia

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